MSM is a naturally occurring nutrient, a sulfur compound, found in normal human's diets and the diets of all other vertebrates. Sulfur is element present in all living organisms. It belongs in the same chemical family which includes oxygen. The highest concentration of MSM is found in Milk. MSM is a natural component of many fruits, vegetables, seafood's, and meat. Food preparation like washing and steaming will reduce the levels of MSM.

While Researchers make no claim for cures, as a food supplement or dietary supplement or dietary ingredient the following conditions seen in the clinic have responded to oral MSM.